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Adapted from Novartis Data on File. 2025.9

% BVC estimates are obtained from a mixed model for repeated measures.9

§Statistically significant between-group comparison at each year for % BVC. All p values are nominal p values.9

 

Annual BVC at 4.6 years (240 weeks)8

 

Group

Core (%)

Extension (%)

Continuous KESIMPTA

−0.34

−0.27

Teriflunomide–KESIMPTA

−0.42

−0.28

Between-group comparison

p=0.115

p=0.666

 

Help Sarah gerust te stellen: met LEQVIO worden LDL-C-doelen effectief en langdurig behaald met slechts twee doses per jaar (na twee initiële doses).1,8,20-22

 

LEQVIO wordt toegediend als subcutane injectie aan het begin van de behandeling, opnieuw na 3 maanden en daarna elke 6 maanden.1

Snelle en langdurige lipidenverlaging leidt tot grotere CV-risicoreductie voor jouw ASCVD-patiënten12

Sarah staat niet alleen in haar strijd – veel patiënten kennen vergelijkbare uitdagingen bij het behouden van hun LDL-C-streefwaarde9
 

Lage therapietrouw aan LLT is een belangrijke factor die patiënten ervan weerhoudt hun LDL-C-streefwaarde te behalen.9
 

Redenen voor lage therapietrouw zijn onder andere:9-11

  • Onvoldoende begrip van ASCVD en de daarmee samenhangende gezondheidsrisico’s
  • Geen zichtbare verbetering van de gezondheid
  • Door de patiënt ervaren bijwerkingen
  • Complicaties en belemmeringen door polyfarmacie
  • Belasting door doseringsschema, onder meer bij hoge doseringsfrequentie
  • Vergeten, vaak door veranderingen in de dagelijkse routine

Nieuwe en verbeterde strategieën zijn nodig om uitdagingen in therapietrouw en in het lipidenmanagement te ondervangen.9

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Sarah - temp

Geen echte patiënt

“Ook al leef ik gezond en neem ik mijn medicijnen, mijn LDL-C blijft te hoog. Soms frustreert dat me. Ik doe mijn best en toch krijg ik niet genoeg grip op mijn risico. Ik weet dat ik HeFH heb en dit mijn hele leven bij me draag. Net als mijn vader zou ik al jong een hartaanval kunnen krijgen. Dat beangstigt me en ik maak me ook zorgen over de gezondheid van mijn zoon."


Sarah is gediagnostiseerd met Heterozygote Familiaire Hypercholesterolemie bij een familieonderzoek 10 jaar geleden.


Sarah is 42 jaar en lerares in het middelbaar onderwijs. Ze is een actieve wandelaar, reist graag en heeft verder geen andere aandoeningen. 


Anamnese en leefstijl

  • Aanhoudend verhoogd LDL-C
  • Gezonde leefstijl
  • Vader HeFH en myocardinfarct  op  57-jarige leeftijd
  • Zoon (16 jaar) HeFH


Bevindingen

  • LDL-C: 3,8 mmol/l
  • BMI: 25 kg/m2
  • Nooit gerookt


Huidige behandeling

  • LDL-C-verlagend:  40 mg rosuvastatine, 10 mg ezetimibe 


LDL-C-streefwaarde

  • Vanwege hoog risico:  LDL-C  < 1,8 mmol/l5,6 

External link  Anchor

    FUTURE study Section 1: What does a dermatologist do?

    A board-certified dermatologist has extensive training, which allows them to accurately diagnose and properly treat more than 3,000 diseases of the skin, hair, and nails as well as cosmetic concerns.

    If you were to watch a dermatologist at work on any given day, you might see them:

    • Treat a baby’s prominent birthmark that threatens the child’s eyesight.
    • Remove a mother’s deadly melanoma at its earliest, most treatable stage.
    • Offer relief for a student whose chronic eczema makes sleep nearly impossible.
    • Diagnose the life-threatening liver condition causing a grandfather’s unbearable itching.
    • Treat the hair loss of a young woman, helping her gain the confidence to search for a job.

    Your dermatologist knows the difference between something small and something major.

    Dermatologists also understand that a skin condition can have a serious impact on your health and well-being. Sometimes, a skin condition is a sign of a serious underlying health issue, and your dermatologist may be the first one to notice it. For example, signs of diabetes and heart disease can show up on the skin.

    Your dermatologist knows that a skin condition doesn’t have to be life-threatening to reduce a person’s quality of life. A skin condition can cause sleep loss, poor self-image, serious depression, or lost productivity. Eczema (aka atopic dermatitis), hair loss that causes scarring, and psoriasis are some conditions that can do this.

     

    Image
    Nancy Andrews

    What is a board-certified dermatologist?

    To become board certified in dermatology requires:

    1. Going to medical school and becoming a doctor
    2. Successfully completing residency training in dermatology
    3. Passing the board exam, a challenging exam that tests the dermatologist on the knowledge and skills acquired during their years of training

    Passing the board exam means the dermatologist is board certified. Board certification comes from one of these three organizations:

    • American Board of Dermatology
    • American Osteopathic Board of Dermatology
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    Clouds

    Accordion Slideshow 1

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    HCP Watching
    Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.

    Accordion Slideshow 2

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    It is a long established fact that a reader will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more-or-less normal distribution of letters, as opposed to using 'Content here, content here', making it look like readable English. Many desktop publishing packages and web page editors now use Lorem Ipsum as their default model text, and a search for 'lorem ipsum' will uncover many web sites still in their infancy. Various versions have evolved over the years, sometimes by accident, sometimes on purpose (injected humour and the like).

    Accordion Slideshow 3

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    Accordion Slideshow 3 Image
    Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.
    Accordion Slideshow 3 Image

    Video
    1 min 16 secs
    Novartis
    Novartis
    Video
    - 06 jun 2024
    1 min 16 secs
    Novartis

    "But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual.

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Lorem ipsum dolor sit amet, consectetur adipiscing elit. Pellentesque consectetur lorem eros, vel tempus lectus accumsan eu. Nam commodo, metus maximus mollis mollis, est eros sagittis nisl, nec bibendum justo quam cursus tellus. Phasellus volutpat aliquet tristique. Donec purus elit, auctor eu quam eu, ultrices auctor erat. Duis lacinia est a ipsum egestas, quis congue ipsum dictum. Fusce condimentum, metus non tempor vehicula, tellus velit gravida massa, sit amet faucibus felis quam non arcu. Nam tincidunt eros sed sem malesuada, eget congue augue bibendum. Nullam et nibh quis nisl hendrerit suscipit. Ut sit amet condimentum lorem, eu interdum quam. Maecenas et varius tortor, id cursus enim. Cras in varius ligula, et cursus neque. Nam ornare, sem ut egestas ultrices, nisl odio scelerisque purus, vitae molestie ante turpis et ipsum. Maecenas fermentum commodo diam, vel consequat eros tincidunt nec. Proin vel arcu nec leo sollicitudin imperdiet ut sed ex.

Aliquam vestibulum, ligula at varius accumsan, orci tortor lobortis nisl, eu condimentum mi mi a velit. Proin laoreet tellus eget metus tristique, ac fringilla enim euismod. Nam eu commodo enim. Maecenas vitae erat id tellus vestibulum dignissim. Morbi sit amet ligula lacinia, facilisis est et, sagittis urna. Donec quis tortor condimentum, tincidunt purus sed, suscipit purus. Mauris commodo est et eros fringilla, sed rutrum elit pulvinar. Nulla facilisi. Pellentesque vel augue dignissim, fringilla arcu et, dignissim orci.

Nunc fermentum, tellus sed placerat faucibus, ante libero imperdiet elit, id fringilla mi erat eu mauris. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Suspendisse iaculis non ligula eu lobortis. Duis aliquam volutpat mauris et pulvinar. Nullam lobortis vulputate est, in tincidunt nibh congue sit amet. Etiam at commodo urna. Aliquam in nunc interdum, mattis mi sit amet, rutrum diam. Phasellus aliquet nulla in magna pretium rhoncus. Maecenas mauris velit, dapibus id risus et, pellentesque aliquet dolor. Sed a condimentum tellus, eu convallis nunc.

Effectieve en langdurige LDL-c verlaging

Leqvio combineert de zekerheid van effectieve en langdurige verlaging (52%**) van het LDL-cholesterol, met de eenvoud van 2 doses per jaar* toegediend door een verpleegkundige of andere zorgprofessional.1-3, Il

Leer meer over hoe Leqvio werkt

 

2

doses per jaar*

pijl
 

Geregeld via politheek of Leqvio Care

pijl

Waarom wil je niet pieken

pijl
 

Priklast telt4,5

priklast

pijl

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