What is Blood Pressure Variability (BPV)?
Blood-pressure variability (BPV) is a complex phenomenon that includes short-term fluctuations occurring within a 24 h period as well as blood pressure changes over more-prolonged periods of time.1
What are the types of Blood Pressure Variability (BPV)?
Short term BPV 1
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Very short-term BPV (beat-by-beat) 1 | Image
Short-term BPV (within 24 h) 1 |
Long term BPV 1
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Long-term BPV (day-by-day) 1 | Image
Long-term BPV (visit-to-visit) 1 |
Improper dosing or titration of antihypertensive therapy (AHT), along with reduced adherence, is one of the causes of long-term blood pressure variability (BPV). 1
What is the clinical relevance of blood pressure variability (BPV)?
Visit-to-visit variability in Systolic blood pressure (SBP) is a strong independent predictor of stroke and coronary events.2
To learn more about the types of blood pressure variability, their mechanisms, and how each is measured, Please click here
The Smoothness Index (SI) and trough-to-peak (T/P) ratio are methods for evaluating 24-hour BP control in hypertension. SI has proven superior to T/P in assessing the homogeneity of BP reduction from antihypertensive therapy.3
BPV: Blood pressure variability.
References
Parati G, Ochoa JE, Lombardi C, Bilo G. Assessment and management of blood-pressure variability. Nature Reviews Cardiology. 2013 Mar;10(3):143-55.
Rothwell PM, Howard SC, Dolan E, O'Brien E, Dobson JE, Dahlöf B, Sever PS, Poulter NR. Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension. The Lancet. 2010 Mar 13;375(9718):895-905.
Parati G, Omboni S, Rizzoni D, Agabiti-Rosei E, Manciaa G. The smoothness index: a new, reproducible and clinically relevant measure of the homogeneity of the blood pressure reduction with treatment for hypertension. Journal of hypertension. 1998 Nov 1;16(11):1685-91.
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